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ISSN : 2287-7991(Print)
ISSN : 2287-8009(Online)
Journal of the Preventive Veterinary Medicine Vol.38 No.1 pp.1-6
DOI : https://doi.org/10.13041/jpvm.2014.38.1.1

Investigation of antibacterial activity of Oenothera biennis L. extract against Salmonella Typhimurium

In-Soo Choi1,†, Woo-Jung Park1, Young-Jo Song1, Jong-Il Shin1, Joong-Bok Lee1, Seung-Yong Park1, Chang-Seon Song1, Sang-Won Lee1, Seung-Seob Lee1, Kun-Ho Seo1, Hyoung-Moon Kim2, Kwang-Jae Lee3, Dong-Woon Kim4
1College of Veterinary Medicine, Konkuk University, Seoul 143-701, Republic of Korea
2College of Commerce and Economics, Konkuk University, Seoul 143-701, Republic of Korea

3Agriproduct Processing Experiment Station, GWARES, Chuncheon 200-182, Republic of Korea
4Swine Science Division, National Institute of Animal Science, Cheonan 331-801, Republic of Korea
Received 16 January 2014, Revised 18 February 2014, Accepted 05 March, 2014

Abstract

Salmonella species is one of the major bacterial agents that causes gastrointestinal disease in pigs. Naturalantimicrobials derived from plants may be alternative therapeutics that could replace currently used antibiotics in the controlof infectious disease. In this study, we assessed the antibacterial activity of Oenothera biennis L. extract against SalmonellaTyphimurium both in vitro and in vivo. O. biennis L. extract had a strong inhibitory effect on S. Typhimurium in vitro, reducingbacterial growth by 87%. For the in vivo experiment, 16 post-weaned pigs were divided into 4 groups consisting of 4 pigs each:an uninfected, untreated negative control group; an untreated positive control group that was infected with S. Typhimurium;and two groups that were infected with S. Typhimurium and treated with either 0.1% or 0.5% O. biennis L. extract. Pigs werefollowed for 21 days after infection, and their body weight, daily gains, feed conversion ratio (FCR), and feed efficiency (FE)were monitored. The pigs treated with O. biennis L. extract had significantly higher daily gains than the positive control group(p<0.05). The O. biennis L. extract-treated pigs also exhibited better weight gain and FE, as well as a lower FCR and lesssevere diarrhea, than the positive controls but these results were not statistically significant. Our study demonstrates that O.biennis L. extract has antibacterial effects against S. Typhimurium, both in vitro and in vivo, and that these antibacterial effectsmay produce better growth performance in pigs infected with S. Typhimurium.

 

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